Rita1 (NM_133908) Mouse Recombinant Protein
Product Specifications
Background
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse RBPJ interacting and tubulin associated 1 (Rita1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1110008J03Rik; AI853657; C86297; Rita
Gene ID
100764
UniProt
Q9D1H0
Accession Number mRNA
NM_133908
Chromosomal Location
5 F
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
27.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rita1
Species
Mouse
Protein ID
NP_598669
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/100764
Uniprot URL
https://www.uniprot.org/uniprot/Q9D1H0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_133908
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_598669
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