Ctdsp1 (NM_153088) Mouse Recombinant Protein
Product Specifications
Background
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity) . Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.[UniProtKB/Swiss-Prot Function]
Synonyms
GIP; Nif3; NLIIF; SCP1
Gene ID
227292
UniProt
P58466, Q5I0X8
Accession Number mRNA
NM_153088
Chromosomal Location
1 C3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
29.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ctdsp1
Species
Mouse
Protein ID
NP_694728
Overview
Purified recombinant protein of Mouse CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (Ctdsp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/227292
Uniprot URL
https://www.uniprot.org/uniprot/P58466
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_153088
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_694728
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