Comt (NM_007744) Mouse Recombinant Protein
Product Specifications
Background
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.[UniProtKB/Swiss-Prot Function]
Synonyms
Comt1; D16Wsu103e; D330014B15Rik
Gene ID
12846
UniProt
O88587
Accession Number mRNA
NM_007744
Chromosomal Location
16 11.4 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
29.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Comt
Species
Mouse
Protein ID
NP_031770
Overview
Purified recombinant protein of Mouse catechol-O-methyltransferase (Comt), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12846
Uniprot URL
https://www.uniprot.org/uniprot/O88587
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007744
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031770
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