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Comt (NM_007744) Mouse Recombinant Protein

Product Specifications

Background

Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse catechol-O-methyltransferase (Comt), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Comt1; D16Wsu103e; D330014B15Rik

Gene ID

12846

UniProt

O88587

Accession Number mRNA

NM_007744

Chromosomal Location

16 11.4 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

29.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Comt

Species

Mouse

Protein ID

NP_031770

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/12846

Uniprot URL

https://www.uniprot.org/uniprot/O88587

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_007744

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_031770

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