Plekhf1 (NM_024413) Mouse Recombinant Protein
Product Specifications
Background
May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8 (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
1810013P09Rik; APPD; LAPF; PHAFIN1; ZFYVE15
Gene ID
72287
UniProt
Q3TB82
Accession Number mRNA
NM_024413
Chromosomal Location
7 B3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
31.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Plekhf1
Species
Mouse
Protein ID
NP_077724
Overview
Purified recombinant protein of Mouse pleckstrin homology domain containing, family F (with FYVE domain) member 1 (Plekhf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/72287
Uniprot URL
https://www.uniprot.org/uniprot/Q3TB82
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024413
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_077724
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