Plekhf1 (NM_024413) Mouse Recombinant Protein

Product Specifications

Background

May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8 (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse pleckstrin homology domain containing, family F (with FYVE domain) member 1 (Plekhf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1810013P09Rik; APPD; LAPF; PHAFIN1; ZFYVE15

Gene ID

72287

UniProt

Q3TB82

Accession Number mRNA

NM_024413

Chromosomal Location

7 B3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

31.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.