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Mapre3 (NM_133350) Mouse Recombinant Protein

Product Specifications

Background

Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (By similarity) . May play a role in cell migration (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse microtubule-associated protein, RP/EB family, member 3 (Mapre3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI790651; EB2; EB3; EBF3; RP3

Gene ID

100732

UniProt

Q6PER3, Q2UZW7

Accession Number mRNA

NM_133350

Chromosomal Location

5 B1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

32 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Mapre3

Species

Mouse

Protein ID

NP_579928

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/100732

Uniprot URL

https://www.uniprot.org/uniprot/Q6PER3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_133350

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_579928

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