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Snrpa (NM_015782) Mouse Recombinant Protein

Selected Variant

PM47593M5

Size: 20 µg

Product Specifications

Background

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse small nuclear ribonucleoprotein polypeptide A (Snrpa), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

C430021M15Rik; Rnu1a-1; Rnu1a1; U1-A; U1A

Gene ID

53607

UniProt

Q62189

Accession Number mRNA

NM_015782

Chromosomal Location

7 A3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

31.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Snrpa

Species

Mouse

Protein ID

NP_056597

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/53607

Uniprot URL

https://www.uniprot.org/uniprot/Q62189

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_015782

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_056597

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