Snrpa (NM_015782) Mouse Recombinant Protein
Selected Variant
PM47593M5
Size: 20 µg
Product Specifications
Background
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse small nuclear ribonucleoprotein polypeptide A (Snrpa), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
C430021M15Rik; Rnu1a-1; Rnu1a1; U1-A; U1A
Gene ID
53607
UniProt
Q62189
Accession Number mRNA
NM_015782
Chromosomal Location
7 A3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
31.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Snrpa
Species
Mouse
Protein ID
NP_056597
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/53607
Uniprot URL
https://www.uniprot.org/uniprot/Q62189
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015782
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056597
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