Nhej1 (NM_029342) Mouse Recombinant Protein
Product Specifications
Background
DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V (D) J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary (PubMed:17360556) . Binds DNA in a length-dependent manner (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
1700029B21Rik; cernunnos; XLF
Gene ID
75570
UniProt
Q3KNJ2
Accession Number mRNA
NM_029342
Chromosomal Location
1 C4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
32.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nhej1
Species
Mouse
Protein ID
NP_083618
Overview
Purified recombinant protein of Mouse non-homologous end joining factor 1 (Nhej1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/75570
Uniprot URL
https://www.uniprot.org/uniprot/Q3KNJ2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_029342
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_083618
Curated Selection
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