Dscr3 (NM_007834) Mouse Recombinant Protein
Product Specifications
Background
Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1) . The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retriever and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling.[UniProtKB/Swiss-Prot Function]
Synonyms
AW538125; Dcra; Dscr3
Gene ID
13185
UniProt
O35075
Accession Number mRNA
NM_007834
Chromosomal Location
16 C4
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
33 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Vps26c
Species
Mouse
Protein ID
NP_031860
Overview
Purified recombinant protein of Mouse VPS26 endosomal protein sorting factor C (Vps26c), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/13185
Uniprot URL
https://www.uniprot.org/uniprot/O35075
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007834
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031860
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
