Pex19 (NM_023041) Mouse Recombinant Protein
Product Specifications
Background
Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) . Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.[UniProtKB/Swiss-Prot Function]
Synonyms
Pxf
Gene ID
19298
UniProt
Q8VCI5
Accession Number mRNA
NM_023041
Chromosomal Location
1 79.54 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
32.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pex19
Species
Mouse
Protein ID
NP_075528
Overview
Purified recombinant protein of Mouse peroxisomal biogenesis factor 19 (Pex19), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19298
Uniprot URL
https://www.uniprot.org/uniprot/Q8VCI5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023041
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_075528
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