Pex19 (NM_023041) Mouse Recombinant Protein

Product Specifications

Background

Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) . Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse peroxisomal biogenesis factor 19 (Pex19), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Pxf

Gene ID

19298

UniProt

Q8VCI5

Accession Number mRNA

NM_023041

Chromosomal Location

1 79.54 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

32.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.