F11r (NM_172647) Mouse Recombinant Protein

Product Specifications

Background

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11447115) . The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (PubMed:11447115) . Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (PubMed:9660867) . Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (By similarity) . Involved in platelet activation (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse F11 receptor (F11r), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

9130004G24; AA638916; ESTM33; JAM; JAM-1; JAM-A; Jcam; Jcam1; Ly106

Gene ID

16456

UniProt

O88792

Accession Number mRNA

NM_172647

Chromosomal Location

1 79.43 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

32.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.