F11r (NM_172647) Mouse Recombinant Protein
Product Specifications
Background
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11447115) . The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (PubMed:11447115) . Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (PubMed:9660867) . Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (By similarity) . Involved in platelet activation (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
9130004G24; AA638916; ESTM33; JAM; JAM-1; JAM-A; Jcam; Jcam1; Ly106
Gene ID
16456
UniProt
O88792
Accession Number mRNA
NM_172647
Chromosomal Location
1 79.43 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
32.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
F11r
Species
Mouse
Protein ID
NP_766235
Overview
Purified recombinant protein of Mouse F11 receptor (F11r), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16456
Uniprot URL
https://www.uniprot.org/uniprot/O88792
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_172647
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_766235
Curated Selection
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