Nosip (NM_025533) Mouse Recombinant Protein
Product Specifications
Background
E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (PubMed:25546391) . Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse nitric oxide synthase interacting protein (Nosip), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2310061K06Rik; CGI-25
Gene ID
66394
UniProt
Q9D6T0
Accession Number mRNA
NM_025533
Chromosomal Location
7 B3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
33.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nosip
Species
Mouse
Protein ID
NP_079809
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66394
Uniprot URL
https://www.uniprot.org/uniprot/Q9D6T0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025533
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079809
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