Rtf2 (NM_025542) Mouse Recombinant Protein
Product Specifications
Background
Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. Interacts with nascent DNA.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse replication termination factor 2 (Rtf2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1700067C04Rik; 2410001C21Rik; 5730427M17Rik; AA589417
Gene ID
66404
UniProt
Q99K95
Accession Number mRNA
NM_025542
Chromosomal Location
2 H3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
33.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rtf2
Species
Mouse
Protein ID
NP_079818
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66404
Uniprot URL
https://www.uniprot.org/uniprot/Q99K95
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025542
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079818
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