Rtf2 (NM_025542) Mouse Recombinant Protein

Product Specifications

Background

Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. Interacts with nascent DNA.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse replication termination factor 2 (Rtf2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1700067C04Rik; 2410001C21Rik; 5730427M17Rik; AA589417

Gene ID

66404

UniProt

Q99K95

Accession Number mRNA

NM_025542

Chromosomal Location

2 H3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

33.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.