Vta1 (NM_025418) Mouse Recombinant Protein
Product Specifications
Background
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies (By similarity) . Involved in the sorting and down-regulation of EGFR.[UniProtKB/Swiss-Prot Function]
Synonyms
1110001D18Rik; 1110059P08Rik; AU040813; C85340; LIP5; SBP1
Gene ID
66201
UniProt
Q9CR26
Accession Number mRNA
NM_025418
Chromosomal Location
10 A2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
33.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Vta1
Species
Mouse
Protein ID
NP_079694
Overview
Purified recombinant protein of Mouse vesicle (multivesicular body) trafficking 1 (Vta1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66201
Uniprot URL
https://www.uniprot.org/uniprot/Q9CR26
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025418
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079694
Curated Selection
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