Ppp2ca (NM_019411) Mouse Recombinant Protein
Product Specifications
Background
PP2A is the major phosphatase for microtubule-associated proteins (MAPs) . PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
PP2A; R75353
Gene ID
19052
UniProt
P63330
Accession Number mRNA
NM_019411
Chromosomal Location
11 B1.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
36.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ppp2ca
Species
Mouse
Protein ID
NP_062284
Overview
Purified recombinant protein of Mouse protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform (Ppp2ca), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19052
Uniprot URL
https://www.uniprot.org/uniprot/P63330
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019411
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062284
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