Fgl1 (NM_145594) Mouse Recombinant Protein

Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed:30580966) . Responsible for LAG3 T-cell inhibitory function (PubMed:30580966) . Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966) . In addition to its role in inhibiting inflammatory immune responses, also plays a role in hepatocytes (By similarity) . Under normal physiological conditions, primarily secreted from hepatocytes and contributes to its mitogenic and metabolic functions (By similarity) .[UniProtKB/Swiss-Prot Function]

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.