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Rdh11 (NM_021557) Mouse Recombinant Protein

Product Specifications

Background

Retinol dehydrogenase with a clear preference for NADP (PubMed:12807874, PubMed:29567832) . Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol (By similarity) (PubMed:12807874) . Exhibits also reductive activity towards toxic lipid peroxidation products such as medium-chain aldehydes trans-2-nonenal, nonanal, and cis-6-nonenal (PubMed:12807874) . Has no dehydrogenase activity towards steroid (PubMed:12807874) . Seems to be required for homeostasis of retinol in liver and testis (PubMed:29567832) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse retinol dehydrogenase 11 (Rdh11), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2610319N22Rik; AI428145; Arsdr1; AU045252; C85936; CGI-82; HCBP12; M42C60; Mdt1; Psdr1; SCALD

Gene ID

17252

UniProt

Q9QYF1

Accession Number mRNA

NM_021557

Chromosomal Location

12 35.51 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

35.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Rdh11

Species

Mouse

Protein ID

NP_067532

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/17252

Uniprot URL

https://www.uniprot.org/uniprot/Q9QYF1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_021557

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_067532

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