Ggh (NM_010281) Mouse Recombinant Protein
Product Specifications
Background
Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. Acts as endopeptidase. Lysosomal enzyme is activated by sulfhydryl compounds.[UniProtKB/Swiss-Prot Function]
Synonyms
Gamma-GH
Gene ID
14590
UniProt
Q9Z0L8
Accession Number mRNA
NM_010281
Chromosomal Location
4 A3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
35.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ggh
Species
Mouse
Protein ID
NP_034411
Overview
Purified recombinant protein of Mouse gamma-glutamyl hydrolase (Ggh), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14590
Uniprot URL
https://www.uniprot.org/uniprot/Q9Z0L8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010281
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034411
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