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Ppp1cb (NM_172707) Mouse Recombinant Protein

Selected Variant

PM47242M5

Size: 20 µg

Product Specifications

Background

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse protein phosphatase 1 catalytic subunit beta (Ppp1cb), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1200010B19

Gene ID

19046

UniProt

P62141

Accession Number mRNA

NM_172707

Chromosomal Location

5 B1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

37.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Ppp1cb

Species

Mouse

Protein ID

NP_766295

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/19046

Uniprot URL

https://www.uniprot.org/uniprot/P62141

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_172707

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_766295

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