Ppp1cb (NM_172707) Mouse Recombinant Protein
Selected Variant
PM47242M5
Size: 20 µg
Product Specifications
Background
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse protein phosphatase 1 catalytic subunit beta (Ppp1cb), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1200010B19
Gene ID
19046
UniProt
P62141
Accession Number mRNA
NM_172707
Chromosomal Location
5 B1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
37.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ppp1cb
Species
Mouse
Protein ID
NP_766295
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19046
Uniprot URL
https://www.uniprot.org/uniprot/P62141
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_172707
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_766295
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