Ubxn2b (NM_026534) Mouse Recombinant Protein
Product Specifications
Background
Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis.[UniProtKB/Swiss-Prot Function]
Synonyms
3110003A22Rik; 6430407D20Rik; AI451665; p37
Gene ID
68053
UniProt
Q0KL01
Accession Number mRNA
NM_026534
Chromosomal Location
4 A1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
37.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ubxn2b
Species
Mouse
Protein ID
NP_080810
Overview
Purified recombinant protein of Mouse UBX domain protein 2B (Ubxn2b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/68053
Uniprot URL
https://www.uniprot.org/uniprot/Q0KL01
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_026534
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_080810
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