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Trub2 (NM_145520) Mouse Recombinant Protein

Product Specifications

Background

Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs) such as COXI and COXIII mt-mRNAs. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse TruB pseudouridine (psi) synthase family member 2 (Trub2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

G430055L02Rik

Gene ID

227682

UniProt

Q91WG3

Accession Number mRNA

NM_145520

Chromosomal Location

2 B

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

36.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Trub2

Species

Mouse

Protein ID

NP_663495

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/227682

Uniprot URL

https://www.uniprot.org/uniprot/Q91WG3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_145520

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_663495

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