Dhdds (NM_026144) Mouse Recombinant Protein
Product Specifications
Background
With NUS1, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) . Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse dehydrodolichyl diphosphate synthase (Dhdds), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
3222401G21Rik; CIT; DS; HDS; W91638
Gene ID
67422
UniProt
Q99KU1
Accession Number mRNA
NM_026144
Chromosomal Location
4 D3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
38.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dhdds
Species
Mouse
Protein ID
NP_080420
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/67422
Uniprot URL
https://www.uniprot.org/uniprot/Q99KU1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_026144
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_080420
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
