Wdr5 (NM_080848) Mouse Recombinant Protein
Product Specifications
Background
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse WD repeat domain 5 (Wdr5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2410008O07Rik; AA408785; AA960360; Big; Big-3
Gene ID
140858
UniProt
P61965
Accession Number mRNA
NM_080848
Chromosomal Location
2 A3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
36.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Wdr5
Species
Mouse
Protein ID
NP_543124
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/140858
Uniprot URL
https://www.uniprot.org/uniprot/P61965
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_080848
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_543124
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