Aen (NM_026531) Mouse Recombinant Protein
Product Specifications
Background
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse apoptosis enhancing nuclease (Aen), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2700083B06Rik; Isg20l1
Gene ID
68048
UniProt
Q9CZI9
Accession Number mRNA
NM_026531
Chromosomal Location
7 D2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
37.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Aen
Species
Mouse
Protein ID
NP_080807
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/68048
Uniprot URL
https://www.uniprot.org/uniprot/Q9CZI9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_026531
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_080807
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