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Sult2b1 (NM_017465) Mouse Recombinant Protein

Product Specifications

Background

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids such as dehydroepiandrosterone. Isoform 1 is required for production of cholesterol sulfate essential for normal skin development whereas isoform 2 produces pregnenolone sulfate, an essential neurosteroid during development of the central nervous system. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse sulfotransferase family, cytosolic, 2B, member 1 (Sult2b1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI326997; BB173635; ST2B1; SULT2B

Gene ID

54200

UniProt

O35400

Accession Number mRNA

NM_017465

Chromosomal Location

7 B3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

38.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Sult2b1

Species

Mouse

Protein ID

NP_059493

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/54200

Uniprot URL

https://www.uniprot.org/uniprot/O35400

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_017465

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_059493

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