Anxa2 (NM_007585) Mouse Recombinant Protein
Product Specifications
Background
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response (By similarity) . Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:22848640) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse annexin A2 (Anxa2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AW215814; Cal1h
Gene ID
12306
UniProt
P07356, Q542G9
Accession Number mRNA
NM_007585
Chromosomal Location
9 38.58 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
38.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Anxa2
Species
Mouse
Protein ID
NP_031611
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12306
Uniprot URL
https://www.uniprot.org/uniprot/P07356
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007585
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031611
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