Thoc6 (NM_001008425) Mouse Recombinant Protein
Product Specifications
Background
Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.Plays a role in apoptosis negative control involved in brain development (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse THO complex 6 (Thoc6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
F830014G06Rik; Wdr58
Gene ID
386612
UniProt
Q5U4D9
Accession Number mRNA
NM_001008425
Chromosomal Location
17 A3.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
37.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Thoc6
Species
Mouse
Protein ID
NP_001008425
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/386612
Uniprot URL
https://www.uniprot.org/uniprot/Q5U4D9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001008425
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001008425
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