Mbnl3 (NM_134163) Mouse Recombinant Protein
Product Specifications
Background
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins (By similarity) . Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse muscleblind like splicing factor 3 (Mbnl3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
A530038J18Rik; AI661274; CHCR; E430034C16Rik; MBLX; MBLX39; MBXL
Gene ID
171170
UniProt
Q8R003, Q542D8, Q8BYC7
Accession Number mRNA
NM_134163
Chromosomal Location
X A5
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
37.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mbnl3
Species
Mouse
Protein ID
NP_598924
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/171170
Uniprot URL
https://www.uniprot.org/uniprot/Q8R003
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_134163
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_598924
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