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Rp2 (NM_133669) Mouse Recombinant Protein

Product Specifications

Background

Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B) . Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse retinitis pigmentosa 2 homolog (Rp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI662636; Rp2h

Gene ID

19889

UniProt

Q9EPK2

Accession Number mRNA

NM_133669

Chromosomal Location

X A1.3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

39.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Rp2

Species

Mouse

Protein ID

NP_598430

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/19889

Uniprot URL

https://www.uniprot.org/uniprot/Q9EPK2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_133669

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_598430

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