Gale (NM_178389) Mouse Recombinant Protein
Product Specifications
Background
Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.[UniProtKB/Swiss-Prot Function]
Synonyms
2310002A12Rik; AI323962
Gene ID
74246
UniProt
Q8R059
Accession Number mRNA
NM_178389
Chromosomal Location
4 D3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
38.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gale
Species
Mouse
Overview
Purified recombinant protein of Mouse galactose-4-epimerase, UDP (Gale), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/74246
Uniprot URL
https://www.uniprot.org/uniprot/Q8R059
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_178389
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