Irf2 (NM_008391) Mouse Recombinant Protein
Product Specifications
Background
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS) ) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse interferon regulatory factor 2 (Irf2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
9830146E22Rik; AI646973; Irf-2
Gene ID
16363
UniProt
P23906, Q3U2Z2
Accession Number mRNA
NM_008391
Chromosomal Location
8 B1.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
39.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Irf2
Species
Mouse
Protein ID
NP_032417
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16363
Uniprot URL
https://www.uniprot.org/uniprot/P23906
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008391
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032417
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