What is the catalog number for Dkk3 (NM_015814) Mouse Recombinant Protein?

The catalog number for Dkk3 (NM_015814) Mouse Recombinant Protein is PM47037M5.

What sizes are available for Dkk3 (NM_015814) Mouse Recombinant Protein?

Dkk3 (NM_015814) Mouse Recombinant Protein is available in the following size(s): 20 µg.

Is Dkk3 (NM_015814) Mouse Recombinant Protein in stock?

Dkk3 (NM_015814) Mouse Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Dkk3 (NM_015814) Mouse Recombinant Protein

Product Specifications

Background

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse dickkopf WNT signaling pathway inhibitor 3 (Dkk3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AW061014; C87148; dkk-3; mDkk-3

Gene ID

50781

UniProt

Q9QUN9

Accession Number mRNA

NM_015814

Chromosomal Location

7 F1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

38.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.