Sord (NM_146126) Mouse Recombinant Protein

Polyol dehydrogenase that catalyzes the reversible NAD (+) -dependent oxidation of various sugar alcohols (By similarity) . Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose (PubMed:6852349) . Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism (By similarity) . May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility and protein tyrosine phosphorylation (PubMed:18799757) . Has no activity on ethanol. Cannot use NADP (+) as the electron acceptor (PubMed:6852349) .[UniProtKB/Swiss-Prot Function]

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.