Mapt (NM_010838) Mouse Recombinant Protein
Product Specifications
Background
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse microtubule-associated protein tau (Mapt), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI413597; AW045860; Mtapt; Tau
Gene ID
17762
UniProt
P10637, Q547J4, Q3UH19, Q8C5K4
Accession Number mRNA
NM_010838
Chromosomal Location
11 E1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
39.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mapt
Species
Mouse
Protein ID
NP_034968
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/17762
Uniprot URL
https://www.uniprot.org/uniprot/P10637
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010838
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034968
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