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Nsfl1c (NM_198326) Mouse Recombinant Protein

Selected Variant

PM46865M5

Size: 20 µg

Product Specifications

Background

Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) . Inhibits the activity of CTSL (in vitro) . Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse NSFL1 (p97) cofactor (p47) (Nsfl1c), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Munc-18c; p47; Stxbp3a

Gene ID

386649

UniProt

Q9CZ44, Q3UVN5

Accession Number mRNA

NM_198326

Chromosomal Location

2 G3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

41 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Nsfl1c

Species

Mouse

Protein ID

NP_938085

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/386649

Uniprot URL

https://www.uniprot.org/uniprot/Q9CZ44

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_198326

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_938085

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