Rragb (NM_001004154) Mouse Recombinant Protein
Product Specifications
Background
Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.[UniProtKB/Swiss-Prot Function]
Synonyms
MGC69750; MGC95567
Gene ID
245670
UniProt
Q6NTA4
Accession Number mRNA
NM_001004154
Chromosomal Location
X F3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
43.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rragb
Species
Mouse
Protein ID
NP_001004154
Overview
Purified recombinant protein of Mouse Ras-related GTP binding B (Rragb), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/245670
Uniprot URL
https://www.uniprot.org/uniprot/Q6NTA4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001004154
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001004154
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