Rragb (NM_001004154) Mouse Recombinant Protein

Product Specifications

Background

Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse Ras-related GTP binding B (Rragb), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

MGC69750; MGC95567

Gene ID

245670

UniProt

Q6NTA4

Accession Number mRNA

NM_001004154

Chromosomal Location

X F3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

43.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.