Fblim1 (NM_133754) Mouse Recombinant Protein
Product Specifications
Background
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse filamin binding LIM protein 1 (Fblim1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2410043F08Rik; Cal; Fblp1; Gt10; migfilin; migfilin (s)
Gene ID
74202
UniProt
Q71FD7
Accession Number mRNA
NM_133754
Chromosomal Location
4 D3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
41 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Fblim1
Species
Mouse
Protein ID
NP_598515
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/74202
Uniprot URL
https://www.uniprot.org/uniprot/Q71FD7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_133754
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_598515
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