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Rccd1 (NM_173445) Mouse Recombinant Protein

Product Specifications

Background

Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.[UniProtKB/Swiss-Prot Function]

Synonyms

5830436H09; E430018M08Rik

Gene ID

269955

UniProt

Q8BTU7

Accession Number mRNA

NM_173445

Chromosomal Location

7 D2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

40.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Rccd1

Species

Mouse

Protein ID

NP_775621

Overview

Purified recombinant protein of Mouse RCC1 domain containing 1 (Rccd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/269955

Uniprot URL

https://www.uniprot.org/uniprot/Q8BTU7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_173445

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_775621

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