Tnfrsf10b (NM_020275) Mouse Recombinant Protein
Product Specifications
Background
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.[UniProtKB/Swiss-Prot Function]
Synonyms
DR5; KILLER; Ly98; MK; TRAILR2; TRICK2A; TRICK2B; TRICKB
Gene ID
21933
UniProt
Q9QZM4
Accession Number mRNA
NM_020275
Chromosomal Location
14 D2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
42.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Tnfrsf10b
Species
Mouse
Protein ID
NP_064671
Overview
Purified recombinant protein of Mouse tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/21933
Uniprot URL
https://www.uniprot.org/uniprot/Q9QZM4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020275
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_064671
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