Pelo (NM_134058) Mouse Recombinant Protein
Product Specifications
Background
Required for normal chromosome segregation during cell division and genomic stability. May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse pelota mRNA surveillance and ribosome rescue factor (Pelo), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AA409897; AI852218
Gene ID
105083
UniProt
Q80X73
Accession Number mRNA
NM_134058
Chromosomal Location
13 D2.2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
43.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pelo
Species
Mouse
Protein ID
NP_598819
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/105083
Uniprot URL
https://www.uniprot.org/uniprot/Q80X73
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_134058
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_598819
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