Nxn (BC004688) Mouse Recombinant Protein
Product Specifications
Background
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR (KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse nucleoredoxin (cDNA clone MGC:7861 IMAGE:3501314), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
L11Jus13
Gene ID
18230
UniProt
P97346
Accession Number mRNA
BC004688
Chromosomal Location
11 45.92 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
68.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nxn
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/18230
Uniprot URL
https://www.uniprot.org/uniprot/P97346
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC004688
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