Napepld (NM_178728) Mouse Recombinant Protein
Product Specifications
Background
Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of these bioactive fatty acid ethanolamides (FAEs), including anandamide (N-arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors (PubMed:14634025) . As a regulator of lipid metabolism in the adipose tissue, mediates the crosstalk between adipocytes, gut microbiota and immune cells to control body temperature and weight. In particular, regulates energy homeostasis by promoting cold-induced brown or beige adipocyte differentiation program to generate heat from fatty acids and glucose (PubMed:25757720) .[UniProtKB/Swiss-Prot Function]
Synonyms
A530089G06; Mbldc1; NAPE-PLD
Gene ID
242864
UniProt
Q8BH82
Accession Number mRNA
NM_178728
Chromosomal Location
5 A3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
45.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Napepld
Species
Mouse
Protein ID
NP_848843
Overview
Purified recombinant protein of Mouse N-acyl phosphatidylethanolamine phospholipase D (Napepld), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/242864
Uniprot URL
https://www.uniprot.org/uniprot/Q8BH82
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_178728
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_848843
Curated Selection
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