Hsd11b2 (NM_008289) Mouse Recombinant Protein
Product Specifications
Background
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.[UniProtKB/Swiss-Prot Function]
Synonyms
11HSD2
Gene ID
15484
UniProt
P51661, Q6NZB9
Accession Number mRNA
NM_008289
Chromosomal Location
8 53.04 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
42.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Hsd11b2
Species
Mouse
Protein ID
NP_032315
Overview
Purified recombinant protein of Mouse hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/15484
Uniprot URL
https://www.uniprot.org/uniprot/P51661
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008289
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032315
Curated Selection
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