Hsd11b2 (NM_008289) Mouse Recombinant Protein

Product Specifications

Background

Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

11HSD2

Gene ID

15484

UniProt

P51661, Q6NZB9

Accession Number mRNA

NM_008289

Chromosomal Location

8 53.04 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

42.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.