Cipc (NM_173735) Mouse Recombinant Protein
Product Specifications
Background
Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK (PubMed:17310242, PubMed:19414601) . However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock (PubMed:25862660) .[UniProtKB/Swiss-Prot Function]
Synonyms
2310044G17Rik; AI842544; AI853744; Kiaa1737; mKIAA1737
Gene ID
217732
UniProt
Q8R0W1, Z4YJJ0
Accession Number mRNA
NM_173735
Chromosomal Location
12 D2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
42.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cipc
Species
Mouse
Protein ID
NP_776096
Overview
Purified recombinant protein of Mouse CLOCK interacting protein, circadian (Cipc), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/217732
Uniprot URL
https://www.uniprot.org/uniprot/Q8R0W1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_173735
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_776096
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