Sec62 (NM_027016) Mouse Recombinant Protein

Product Specifications

Background

Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER) . Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse SEC62 homolog (S. cerevisiae) (Sec62), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

3100002M17Rik; AI844545; AW545092; Dtrp1; HTP1; Tloc1

Gene ID

69276

UniProt

Q8BU14

Accession Number mRNA

NM_027016

Chromosomal Location

3 A3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

45.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.