Sec62 (NM_027016) Mouse Recombinant Protein
Product Specifications
Background
Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER) . Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse SEC62 homolog (S. cerevisiae) (Sec62), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
3100002M17Rik; AI844545; AW545092; Dtrp1; HTP1; Tloc1
Gene ID
69276
UniProt
Q8BU14
Accession Number mRNA
NM_027016
Chromosomal Location
3 A3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
45.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Sec62
Species
Mouse
Protein ID
NP_081292
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/69276
Uniprot URL
https://www.uniprot.org/uniprot/Q8BU14
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_027016
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_081292
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